What is PTD-DBM?
PTD-DBM is a synthetic peptide with two parts: a protein transduction domain (PTD) that helps it enter cells, and a Dishevelled-binding motif (DBM). It blocks the binding of the protein CXXC5 to Dishevelled, which normally holds back the Wnt/beta-catenin signalling pathway. It was developed by Kang-Yell Choi’s group at Yonsei University, South Korea. In their mouse studies, topical PTD-DBM promoted hair regrowth and new hair follicle formation after wounding (Lee et al., Journal of Investigative Dermatology, 2017).
PTD-DBM product specifications
- Compound: PTD-DBM
- Structure: protein transduction domain linked to a Dishevelled-binding motif
- Molecular weight: about 3082.7 g/mol
- CAS number: 1609454-11-6
- Vial size: 5mg
Regulatory status
PTD-DBM is not an approved medicine in the US, UK, EU or Canada. Published results come from animal and cell studies, and its effects in humans have not been established. This product is sold for laboratory research use only.
Related research peptides
- GHK-Cu is a copper peptide studied in skin and hair research.
Handling and research-use notice
Store and handle this material as stated on the label and certificate of analysis for your batch; see our guide to storing research peptides. This product is sold for laboratory research use only. It is not a medicine or supplement and is not for human or veterinary use.
