What is MOTS-c?
MOTS-c is a peptide of 16 amino acids with the sequence MRWQEMGYIFYPRKLR. Unlike most peptides, it is encoded in mitochondrial DNA, by a short open reading frame inside the 12S rRNA gene. It was first described in 2015 by Lee and colleagues in the journal Cell Metabolism. The name stands for “mitochondrial open reading frame of the 12S rRNA type-c”.
MOTS-c product specifications
- Compound: MOTS-c
- Sequence: MRWQEMGYIFYPRKLR (16 amino acids)
- Molecular formula: C101H152N28O22S2
- Molecular weight: about 2174.7 g/mol
- CAS number: 1627580-64-6
- Vial sizes: 10mg, 20mg and 40mg
MOTS-c in laboratory research
MOTS-c is studied as one of a small group of mitochondrial-derived peptides, mainly in cell and animal models of metabolism. It remains investigational, and results from those models cannot be taken as evidence of safety or effect in people.
Regulatory status
MOTS-c is not an approved medicine anywhere. This product is sold for laboratory research use only.
Related research compounds
- Humanin is another mitochondrial-derived peptide.
- SS-31 is a synthetic peptide studied in mitochondrial research.
- NAD+ is a coenzyme central to mitochondrial metabolism.
Available sizes: 10mg, 20mg and 40mg
MOTS-c is offered in three vial sizes: 10mg, 20mg and 40mg. All contain the same peptide. The figure is the total amount of peptide in the vial, supplied as a dry (lyophilised) powder; it is not a concentration, so a larger vial is not “stronger”, it simply holds more material. Tell us which size you need when you contact us on Telegram or by email.
Choose the size from the options on this page, then contact us on Telegram or by email for availability.
Handling and research-use notice
Store and handle this material as stated on the label and certificate of analysis for your batch; see our guide to storing research peptides. MOTS-c from Moh Peptides Supply is sold for laboratory research use only. It is not a medicine or supplement and is not for human or veterinary use.



