What is Adipotide?
Adipotide, also called FTPP (fat-targeted proapoptotic peptide), is a peptidomimetic with two parts. A targeting sequence, CKGGRAKDC, binds prohibitin on blood vessels that supply white fat tissue. It is linked to a D-amino-acid sequence, D(KLAKLAK)2, that triggers cell death in the cells it reaches.
It was first described in mice (Kolonin et al., Nature Medicine, 2004) and later studied in obese rhesus monkeys (Barnhart et al., Science Translational Medicine, 2011). The monkey study reported dose-dependent effects on kidney function.
Adipotide product specifications
- Compound: Adipotide (FTPP)
- Structure: CKGGRAKDC-GG-D(KLAKLAK)2 (targeting motif, glycine linker, D-amino-acid proapoptotic motif)
- Vial size: 10mg
Regulatory status
Adipotide is not an approved medicine in the US, UK, EU or Canada. This product is sold for laboratory research use only.
Related research compounds
- AOD 9604 is a growth hormone fragment studied in fat metabolism research.
- 5-Amino-1MQ is a small molecule studied in fat-cell metabolism.
Handling and research-use notice
Store and handle this material as stated on the label and certificate of analysis for your batch; see our guide to storing research peptides. This product is sold for laboratory research use only. It is not a medicine or supplement and is not for human or veterinary use.
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