AICAR (50mg)

What is AICAR?

AICAR (5-aminoimidazole-4-carboxamide ribonucleoside, also called acadesine) is a nucleoside, not a peptide. Inside cells it is converted to ZMP, which mimics AMP and activates AMP-activated protein kinase (AMPK), an enzyme that senses cellular energy levels. It is widely used as a research tool for studying AMPK signalling in cell and animal models.

AICAR product specifications

• Compound: AICAR (acadesine)
• Type: nucleoside AMPK activator
• Molecular formula: C9H14N4O5
• Molecular weight: about 258.2 g/mol
• CAS number: 2627-69-2
• Vial size: 50mg

Regulatory status

AICAR is not an approved medicine in the US, UK, EU or Canada. Acadesine was tested in clinical trials but was not approved. It is on the World Anti-Doping Agency (WADA) Prohibited List as a metabolic modulator. This product is sold for laboratory research use only.

Related research compounds

• MOTS-c is a mitochondrial peptide studied in relation to AMPK signalling.
• 5-Amino-1MQ is another small molecule studied in metabolic research.

Handling and research-use notice

Store and handle this material as stated on the label and certificate of analysis for your batch; see our guide to storing research peptides. This product is sold for laboratory research use only. It is not a medicine or supplement and is not for human or veterinary use.